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. Author manuscript; available in PMC: 2014 Nov 21.
Published in final edited form as: Dev Cell. 2013 Sep 5;26(5):496–510. doi: 10.1016/j.devcel.2013.08.005

Figure 7. MP-GAP controls RhoA zone formation in the absence of the centrosomal asters.

Figure 7

In control cells, RhoA zone dimensions are dominantly specified by the centrosomal asters. MP-GAP inhibition does not increase RhoA zone dimensions when the asters are present, but it does lead to the formation of large protrusions. In the absence of the centrosomal asters, MP-GAP inhibition broadens the equatorial RhoA zone indicating that RhoA zone dimensions are controlled by MP-GAP mediated RhoA flux.