Figure 6.
Analysis of VDR recruitment of members of the SRC/p160 family of NR coactivators in response to 120 nM 1, 25D3. Data are represented as the average fold interaction ± SEM (n = 4). Data are normalized to VDR in the absence of coregulators. Asterisks above the bars indicate a significant interaction between VDR and SRC-1, GRIP1, or ACTR compared with the VDR alone control. ***, P < .001; **, P < .01; *, P < .05. Asterisks above the brackets indicate a significant difference in VDR-SRC/p160 interaction in the presence and absence of RXRWT.