Table 2.
Metabolic laboratory findings from each experimental mice group
| Laboratory findings | Lean | ob/ob | ob/ob + MK-0626 (1.5 mg/kg) | ob/ob + MK-0626 (3 mg/kg) |
| Glucose (mg/dL) | 141 ± 43.8 | 349 ± 15.7 | 288 ± 17.6a | 247 ± 42.5b |
| Insulin (μU/mL) | 1.83 ± 0.61 | 11.54 ± 0.59 | 8.42 ± 1.03a | 7.83 ± 0.44b |
| HOMA score | 0.63 ± 0.06 | 9.96 ± 2.32 | 5.98 ± 0.52a | 4.78 ± 0.166b |
| ALT (U/L) | 43.3 ± 10.3 | 590 ± 109.5 | 278 ± 70.5a | 272.5 ± 131.5a |
| Adiponectin (μg/mL) | 31.15 ± 2.07 | 34.57 ± 1.25 | 37.86 ± 3.40 | 39.90 ± 1.28a |
a
P < 0.05,
b
P < 0.01 vs ob/ob mice group. HOMA: Homeostatic model assessment; ALT: Alanine aminotransferase.