Skip to main content
. Author manuscript; available in PMC: 2014 Nov 21.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Jul 8;(3):CD007235. doi: 10.1002/14651858.CD007235.pub2
Methods RCT.
Participants Singleton (and 3 twin) gestations; uterine contractions or symptoms suggestive of preterm labor at 24 to 33 6/7 weeks. N = 100
Interventions TVU CL knowledge or not (the control group did receive TVU CL, but results were blinded to managing physicians)
Time TVU CL results available: not specified.
Protocol for TVU knowledge group: yes.
Outcomes Primary: time from initial evaluation to discharge.
Notes Intention to treat; 97% singletons; protocol for management of TVU CL group, which included management based on FFN for women with CL 20 to 29 mm
Short TVUCL ( < 20mm): 11/51 (22%) in knowledge group; 7/49 (15%) in the control group
Risk of bias
Bias Authors’ judgement Support for judgement
Random sequence generation (selection bias) Low risk Computer-generated random numbers.
Allocation concealment (selection bias) Low risk Numbered, sealed opaque envelopes.
Blinding (performance bias and detection bias)
All outcomes
High risk Women and physicians knew which group was randomized to ‘knowledge’ or ‘no knowledge’
Incomplete outcome data (attrition bias)
All outcomes
Low risk Intention-to-treat analyses.
Selective reporting (reporting bias) Low risk Primary outcome time from evaluation to discharge.