TABLE 3b.

Rectal Cancer: Site-Specific Factors (SSFs) Description, Codes, and Applicability, SEER 18, 2010 Cases

	Known			Unknown			Total
	Codes	N	%	Codes	N	%	N
SSF 1: Carcinoembryonic Antigen (CEA)	010, 020, 030	5214	53.9	997, 998, 999	4464	46.1	9678
SSF 2: Clinical Assessment of Regional Lymph Nodes	000-120	7626	78.8	200, 400, 999	2052	21.2	9678
2a. Select Reg LN eval = 0, 1, 5, 9	000-120	3549	72.9	200, 400, 999	1317	28.1	4866
2b. Select Reg LN eval = 0, 1, 5, 9, and CS LN = 100-300, 800	010-120	654	58.2	000, 200, 400, 999	469	41.8	1123
SSF 3: Carcinoembryonic Antigen (CEA) Lab Value	000-980	5194	53.7	997, 998, 999	4484	46.3	9678
SSF 4: Tumor Deposits	000-081	6281	64.9	990, 998, 999	3397	35.1	9678
4a. Selected surgery codes 30-80	000-081	5081	82.8	990, 998, 999	1053	17.2	6134
SSF 6: Circumferential Resection Margin (CRM)	000-981, 990-996	4972	51.4	998, 999	4706	48.6	9678
6a. Selected surgery codes 30-80	000-981, 990-996	4525	73.8	998, 999	1609	26.2	6134
SSF 8: Perineural Invasion	000-010	6263	64.7	998, 999	3415	35.3	9678
8a.Selected surgery codes 30-80	000-010	5043	82.2	998, 999	1091	17.8	6134
SSF 9:KRAS	010-020	716	7.4	997, 998, 999	8962	92.6	9678
9a. KRAS stage IV only	010-020	362	21.3	997, 998, 999	1340	78.7	1702

Source: National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) Program: SEER 18 geographic areas: States of Connecticut, New Mexico, Utah, California (4 areas: San-Francisco, San Jose-Monterey, Los Angeles, Greater California), Hawaii, Iowa, New Jersey, Louisiana, Kentucky, Georgia (3 areas: Atlanta, Rural Georgia, and remainder of the state), Alaska Native Registry, and metropolitan areas of Detroit, Michigan and Seattle (Western Washington), Washington.

LN: Lymph nodes; Reg: Regional; eval: evaluation; CS: Collaborative Stage

Note: there were no cases for not applicable (codes 988 or blank).