Table 2.
Serum fatty acid status and adjusted odds ratios of current suicide risk at 1st trimester of pregnancy, Rio de Janeiro, 2009-2011 (n=234)
| Fatty acids a | Current Suicide Risk | Unadjusted | Adjusted* | ||
|---|---|---|---|---|---|
|
| |||||
| No (n=188) Mean (SD) |
Yes (n=46) Mean (SD) |
Odds Ratio (95% CI)b |
Odds Ratio (95% CI)b |
||
| Omega-6 polyunsaturated fatty acids (%) | |||||
| LA | 18:2 n-6 | 31.00 (3.43) | 30.44 (3.68) | 0.85 (0.62-1.17) | 0.78 (0.56-1.08) |
| 18:3 n-6 | 0.33 (0.13) | 0.37 (0.14) | 1.30 (0.95-1.77) | 1.26 (0.91-1.74) | |
| 20:2 n-6 | 0.32 (0.07) | 0.31 (0.06) | 0.87 (0.60-1.25) | 0.80 (0.53-1.21) | |
| 20:3 n-6 | 1.88 (0.46) | 1.94 (0.44) | 1.12 (0.82-1.53) | 1.21 (0.86-1.69) | |
| AA | 20:4 n-6 | 9.17 (1.56) | 9.62 (1.89) | 1.34 (0.96-1.87) | 1.45 (1.02-2.07) |
| AdA | 22:4 n-6 | 0.39 (0.09) | 0.41 (0.10) | 1.29 (0.93-1.79) | 1.43 (1.01-2.04) |
| 22:5 n-6 | 0.39 (0.09) | 0.41 (0.10) | 1.10 (0.80-1.51) | 1.29 (0.91-1.83) | |
| n-6 HUFA | 78.07 (3.89) | 78.76 (3.85) | 1.22 (0.85-1.77) | 1.17 (0.81-1.69) | |
| Omega-3 polyunsaturated fatty acids (%) | |||||
| 18:3 n-3 | 0.63 (0.14) | 0.62 (0.15) | 0.96 (0.70-1.32) | 0.80 (0.56-1.14) | |
| EPA | 20:5 n-3 | 0.42 (0.22) | 0.44 (0.20) | 1.09 (0.80-1.49) | 1.10 (0.78-1.56) |
| DPA | 22:5 n-3 | 0.53 (0.11) | 0.55 (0.14) | 1.20 (0.86-1.66) | 1.23 (0.87-1.73) |
| DHA | 22:6 n-3 | 2.46 (0.56) | 2.42 (0.58) | 0.94 (0.66-1.32) | 1.07 (0.75-1.52) |
| n-3 HUFA | 21.93 (3.89) | 21.24 (3.85) | 0.82 (0.57-1.80) | 0.85 (0.59-1.23) | |
| Monounsaturated fatty acids (%) | |||||
| 16:1 n-7 | 1.63 (0.60) | 1.67 (0.57) | 1.07 (0.79-1.45) | 1.08 (0.79-1.48) | |
| 18:1 n-9 | 15.98 (1.81) | 15.91 (1.75) | 0.96 (0.70-1.34) | 1.06 (0.75-1.50) | |
| 18:1 n-7 | 1.69 (0.21) | 1.70 (0.25) | 1.04 (0.75-1.44) | 1.24 (0.87-1.76) | |
| 20:1 n-9 | 0.15 (0.03) | 0.15 (0.03) | 0.90 (0.63-1.29) | 0.99 (0.66-1.47) | |
| 24:1 n-9 | 1.12 (0.19) | 1.12 (0.20) | 0.99 (0.72-1.36) | 1.16 (0.81-1.64) | |
| Total | 20.58 (2.32) | 20.56 (2.11) | 0.99 (0.72-1.37) | 1.11 (0.79-1.57) | |
| Saturated fatty acids (%) | |||||
| 14:0 | 0.68 (0.26) | 0.66 (0.26) | 0.95 (0.69-1.29) | 0.89 (0.63-1.25) | |
| 16:0 | 21.90 (1.75) | 21.93 (1.72) | 1.01 (0.74-1.39) | 0.96 (0.68-1.35) | |
| 18:0 | 7.47 (0.68) | 7.43 (0.62) | 0.93 (0.66-1.31) | 0.92 (0.62-1.35) | |
| 20:0 | 0.31 (0.05) | 0.32 (0.05) | 1.12 (0.82-1.54) | 1.34 (0.93-1.91) | |
| 22:0 | 0.85 (0.13) | 0.87 (0.20) | 1.19 (0.87-1.61) | 1.17 (0.85-1.62) | |
| 24:0 | 0.73 (0.12) | 0.74 (0.16) | 1.12 (0.81-1.55) | 1.08 (0.77-1.50) | |
| Total | 31.94 (1.68) | 31.95 (1.49) | 1.01 (0.73-1.39) | 0.94 (0.67-1.32) | |
a
Fatty acids are expressed as percentage of total serum fatty acids;
b
Odds ratios of current suicide risk per standard deviation for each fatty acids,
*
adjusted by parity, marital status and gestational week, using binary logistic regression;
Abbreviations: SD = standard deviation; CI = confidence interval; LA = linolenic acid; AA = arachidonic acid; AdA = adrenic acid; HUFA = highly unsaturated fatty acid; EPA = eicosapentaenoic acid; DPA = docosapentaenoic acid; DHA = docosahexaenoic acid