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. 2014 Nov 13;16(12):1091–1097. doi: 10.1007/s12094-014-1244-0
4th step: IMH to carcinomas and specific adenocarcinomas
Tumor Specific staining
Urothelial origin p63, thrombomodulin, uroplakin
Mucinous ovarian WT-1
Serous ovarian WT-1, BerEp4; Ca 125; RE; mesothelin
Lung subtype adenocarcinoma TTF-1; Surf-A y B
Lung no adenocarcinoma CK-7
Small cell lung cancer Cromogranin A, sinaptofisine
Breast RE; RPg; HER.2; mamoglobin; GCDFP15
Endometrial RE; vimentine
Mesothelioma WT-1; calretinin; mesothelin; CK5
Germinal tumors Falc; AFP; βHCG; CD30; OCT4
Thyroid Thyroglobulin; TTF-1
Prostate PSA; falc
No urothelial kidney CD10; vimentine; gp200
Colorectal CX2; CEA
Hepatocellular carcinoma Herpar1; CD10; pCEA
Pancreas/biliary tract CDX2; CK7; Ca 19.9; mesothelin; trifoil factor 1
Neuroendocrine Cromogranin A; sinaptofisine; CD56; PGP9