Figure 3.

Prediction corrected-visual predictive check (PC-VPC) for norepinephrine concentrations vs. time in minutes. The green lines depict the 5th, 50th and 95th percentiles of observed data; the areas represent the 95% confidence interval around the simulated percentiles. The blue colour represents the 5th and 95^th percentile of the predicted concentration vs. time while the pink colour represents the median predicted concentration vs. time. Time 0 min represents the starting time of norepinephrine infusion