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Dosing simulations depicting the increases in norepinephrine concentration and haemodynamic responses as a function of infusion rate in children of different bodyweights and ages for patients with a number of organ dysfunctions ≤3 or ≥4, respectively. Body weight (kg): 
3, age (months): 0.462; body weight (kg): 
10, age (months): 12; body weight (kg): 
20, age (months): 72; body weight (kg): 
40, age (months): 144; body weight (kg): 
70, age (months): 300
