Table 2.
Characteristics of ASD participants according to brain lactate statusa
| ASD Group | Age mean (range) | Adult >18y N (%) | Female N (%) | FSIQ mean (range) | ASD Subtype b | ADOS scores (SA/RBB/total) c | ADOS module N (%) |
|---|---|---|---|---|---|---|---|
| Lactate doublets present (n = 10) | 31.7 (5–59y) | 8 (80%) | 2 (20%) | 109 (79–132) | AD 5 (50%) Asp 3 (30%) PDD 2 (20%) |
9.6/2.3/11.9 | module 2 0 (0%) module 3 2 (20%) module 4 6 (60%) not tested 2 (20%) |
| Lactate doublets absent (n = 65) | 20.2 (5–60y) | 33 (51%) | 15 (23%) | 108 (52–146) | AD 29 (45%) Asp 21 (32%) PDD 15 (23%) |
9.4/1.9/11.3 | module 2 5 (8%) module 3 22 (34%) module 4 28 (43%) not tested 10 (15%) |
a
Percentages reflect the number of participants within the lactate-positive group or lactate-negative group with a particular characteristic
b
AD = Autistic Disorder; Asp = Asperger’s Disorder; PDD = Pervasive Developmental Disorder Not Otherwise Specified
c
SA = Social Affect; RRB = Restricted Repetitive Behavior; ADOS was not completed in 12 ASD participants for the following reasons: 1 participant displayed elective mutism; 11 participants had scheduling conflicts. All participants, however, were evaluated in detail clinically by a psychologist, psychiatrist, or neurologist with expertise in the diagnosis of ASD and met DSM-IV-TR criteria for ASD.