Table 1.

Statistical results

Figure referenced	Parameters	Statistical analysis	Brain region	T value			p value
				Sex	treat	Inter	Sex	treat	Inter
2B	[18F] FPEB binding potential	two-way ANOVA	OB	T = 1.87	T = 0.96	T= 1.35	p = 0.067	p = 0.344	p = 0.183
			CTX	T = −0.62	T = −1.02	T = 0.89	p = 0.538	p = 0.315	p = 0.377
			HTH	T = 0.80	T = −0.59	T= 0.79	p = 0.429	p = 0.557	p = 0.435
			S	T = 0.45	T = −1.25	T= −0.11	p = 0.654	p = 0.216	p = 0.909
			HC	T = −0.72	T = −2.33	T= 0.16	p = 0.472	p = 0.023	p = 0.873
			W	T = 0.09	T = −1.22	T = 0.04	p = 0.926	p = 0.228	p = 0.967
3B	[11C] PBR28 binding potential	Two-way ANOVA	OB	T = −0.72	T = 0.88	T = −1.35	p = 0.473	p = 0.380	p = 0.183
			CTX	T = 0.12	T = −0.18	T= 0.8	p = 0.909	p = 0.856	p = 0.427
			HTH	T = 0.14	T = 1.58	T = 0.11	p = 0.886	p = 0.120	p = 0.910
			S	T = −0.52	T = 1.88	T = 0.46	p = 0.606	p = 0.067	p = 0.650
			HC	T = −0.46	T = 0.36	T = −0.20	p = 0.649	p = 0.719	p = 0.845
			CRBL	T = 0.14	T = 1.48	T = 0.43	p = 0.888	p = 0.145	p = 0.736
			W	T = −0.06	T = 0.93	T = 0.51	p = 0.950	p = 0.354	p = 0.614
4A	Weight	Two-way ANOVA	---	T = −6.23	T = 1.56	T = −0.84	p < 0.001	p = 0.122	p = 0.404
4B	Time spent in light box	Two-way ANOVA	---	T = −0.19	T = 3.29	T = 0.71	p = 0.849	p = 0.001	p = 0.480
4C	Alternance		---	T = 0.41	T = 1.98	T = 0.79	p = 0.680	p = 0.051	p = 0.434
4C	Average time/event	Two-way ANOVA	---	T = −0.40	T = 2.49	T = 0.92	p = 0.688	p = 0.015	p = 0.361
4D	Grasping time	Two-way ANOVA	---	T = −1.52	T = −1.36	T = −0.45	p = 0.132	p = 0.176	p = 0.650

Abbreviations: CTX, cortex; CRBL, cerebellum; F-LPS, female-LPS; F-Sal, female-saline; HC, hippocampus; HTH, hypothalamus; M-Sal, male-saline; M-LPS, male-LPS; OB, olfactory bulb; S, striatum; W, whole brain; [¹¹C]PBR28, peripheral benzodiazepine receptor 28; [¹⁸F]FPEB, [¹⁸F]fluoro-5-(2-pyridinylethynyl)benzonitrile