Figure 4. L-Aspartate and CQ uptake by Xenopus oocytes expressing PfCRT.

[¹⁴C]L-aspartate uptake (a) and [³H]CQ uptake (b) in n.i. (non-injected) oocytes and in oocytes expressing PfCRT^CQS, PfCRT^CQR or rat GLAST. Uptake is shown as the means + S.E.M. from nine separate experiments, within which measurements were made from ten oocytes per treatment. (c) Effect of unlabelled L-aspartate (1 and 2 mM) on the uptake of [³H]CQ into n.i. oocytes (white bars) and oocytes expressing PfCRT^CQS (grey bars) or PfCRT^CQR (black bars). Uptake is shown as the means + S.E.M. from three separate experiments, within which measurements were made from ten oocytes per treatment.