Table 1. Cav-1 KO ASMCs show higher intracellular polyamine levels compared with WT cells.

Treatment with DFMO for 2 days strongly attenuates cellular Put and Spd contents both in WT and Cav-1 KO cells. Values are presented as mean±S.E.M. of three observations in each group. ** and *** represent P<0.01 and P<0.001 for Cav-1 KO compared with WT cells, respectively. ^### represents P<0.001 for DFMO-treated compared with control cells.

	Putrescine (nmol/mg protein)		Spermidine (nmol/mg protein)		Spermine (nmol/mg protein)
	Ctrl	DFMO	Ctrl	DFMO	Ctrl	DFMO
WT	0.69±0.02	0.00 ###	5.1±0.18	0.82±0.03###	2.50±0.14	2.53±0.43
Cav-1 KO	1.66±0.08***	0.00 ###	5.73±0.30	0.39±0.02***###	2.79±0.28**	3.57±0.27