Table 2.

Clinical features of breast cancer (all ages)

Symptom in the preceding year	Cases, n (%) n = 3994	Controls, n (%) n = 16 873	Likelihood ratio (95% CI)	Odds ratio in multivariable analysis (95% CI)
Breast lump	1762 (44.1)	132 (0.8)	56 (47 to 67)	110 (88 to 150)
Breast pain	95 (2.4)	127 (0.8)	3.2 (2.4 to 4.1)	4.2 (3.0 to 6.0)
Nipple retraction	40 (1.0)	9 (0.1)	19 (9.1 to 39)	26 (10 to 64)
Nipple discharge	41 (1.0)	15 (0.1)	12 (6.4 to 21)	19 (8.6 to 41)

Note: All associations in the model have P < 0.001.