Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Assessment of thermostability for WT and mutant human GST-GCK proteins. Logistic regression modelling was used to fit an activity curve to each protein in (A). Data were normalized to the baseline level of activity for each protein at 40°C. Each point represents mean activity ± SEM (n = 3 experiments except for WT and p.T342P n = 10 and p.D160N n = 6). The raw residuals, defined as the difference between observed and predicted values, for all proteins are shown in (B).
