Figure 1.

Cross-sectional subcortical white matter analysis DTI metrics results. Subcortical white matter volumes of interest analysis results. Figure shows volumes of interest with either significant reduced mean diffusivity (MD), fractional anisotropy (FA), axial diffusivity (AD) and/or radial diffusivity (RD) in sporadic CJD compared with controls after correction for multiple comparisons (FDR). Colour-scale shows P-values of significance. Orientation is radiologic (right brain is left side of image). There were no subcortical white matter volumes of interest showing significantly increased DTI metrics in sporadic CJD versus controls after correction for multiple comparisons (FDR).