Table I.
Genes overexpressed in meningioma and schwannoma when compared with their respective control tissue.
| Gene | Database | Chromosome | C-M | N-S | M-S | P-value |
|---|---|---|---|---|---|---|
| CDH1 | NM_004360 | 16q22.1 | 5.4 | 5.8 | −1.0 | 8.35E-09 |
| PDGFD | NM_025208 | 11q22.3 | 4.4 | 6.2 | −1.1 | 7.48E-13 |
| SLIT2 | NM_004787 | 4p15.2 | 3.6 | 5.8 | −1.1 | 2.02E-13 |
| HLA-DPA1 | NM_033554 | 6p21.3 | 2.9 | 3.9 | −1.1 | 5.24E-07 |
| PAPPA | NM_002581 | 9q33.2 | 2.8 | 3.8 | −1.1 | 3.68E-06 |
| TREM2 | NM_018965 | 6p21.1 | 2.7 | 5.5 | −1.3 | 2.8E-12 |
| HLA-DPA1 | NM_033554 | 6p21.3 | 2.6 | 4.1 | −1.2 | 5.24E-07 |
| HPGDS | NM_014485 | 4q22.3 | 2.6 | 2.4 | −1.1 | 3.83E-07 |
| GPR34 | NM_001097579 | Xp11.4 | 2.6 | 12.0 | −1.5 | 9.9E-11 |
| CX3CR1 | NM_001337 | 3p21|3p21.3 | 2.5 | 5.7 | −1.2 | 2.15E-07 |
| ANKRD22 | NM_144590 | 10q23.31 | 2.5 | 7.3 | −1.4 | 1.04E-06 |
| C3 | NM_000064 | 19p13.3-p13.2 | 2.4 | 2.6 | −1.2 | 5.77E-05 |
| CYBB | NM_000397 | Xp21.1 | 2.4 | 4.1 | −1.2 | 1.11E-07 |
| LGALS3BP | NM_005567 | 17q25 | 2.4 | 2.9 | −1.1 | 4.67E-13 |
| WIPI1 | NM_017983 | 17q24.2 | 2.4 | 2.0 | −1.0 | 2.55E-12 |
| APOBEC3C | NM_014508 | 22q13.1 | 2.4 | 2.5 | −1.1 | 3.35E-08 |
| C3AR1 | NM_004054 | 12p13.31 | 2.4 | 4.8 | −1.2 | 4.43E-09 |
| FCGBP | NM_003890 | 19q13.1 | 2.3 | 9.7 | −1.3 | 1.03E-11 |
| FRAS1 | NM_025074 | 4q21.21 | 2.3 | 3.2 | −1.2 | 7.42E-08 |
| FLRT3 | NM_198391 | 20p11 | 2.3 | 3.8 | −1.2 | 1.76E-05 |
| FCGR1A | NM_000566 | 1q21.2–q21.3 | 2.3 | 4.3 | −1.3 | 1.66E-08 |
| MET | NM_001127500 | 7q31 | 2.3 | 4.9 | −1.3 | 1.22E-08 |
| ITPR3 | NM_002224 | 6p21 | 2.3 | 3.7 | −1.1 | 3.69E-12 |
| FCGR1B | NM_001017986 | 1p11.2 | 2.3 | 2.9 | −1.2 | 4.14E-08 |
| ALCAM | NM_001627 | 3q13.1 | 2.2 | 2.5 | −1.0 | 4.26E-09 |
| HLA-DPB1 | NM_002121 | 6p21.3 | 2.2 | 4.6 | −1.3 | 1.75E-07 |
| LAMB1 | NM_002291 | 7q22 | 2.2 | 2.0 | −1.2 | 4.57E-07 |
| C8orf84 | NM_153225 | 8q21.11 | 2.2 | 2.6 | −1.2 | 8.11E-06 |
| SLFN12 | NM_018042 | 17q12 | 2.2 | 2.3 | −1.2 | 4.14E-10 |
| FCGR1A | NM_000566 | 1q21.2–q21.3 | 2.2 | 3.1 | −1.2 | 1.66E-08 |
| LHFPL2 | NM_005779 | 5q14.1 | 2.1 | 2.3 | −1.1 | 8.13E-09 |
| MS4A6A | NM_152852 | 11q12.1 | 2.1 | 4.5 | −1.3 | 4.8E-08 |
| CD84 | NM_001184879 | 1q24 | 2.1 | 2.7 | −1.2 | 3.38E-09 |
| TRIM22 | NM_006074 | 11p15 | 2.1 | 2.2 | −1.1 | 2.09E-09 |
| CD4 | NM_000616 | 12pter-p12 | 2.1 | 2.5 | −1.1 | 1.69E-07 |
| CSF1R | NM_005211 | 5q32 | 2.1 | 3.8 | −1.2 | 5.21E-08 |
| GFRA1 | NM_005264 | 10q26.11 | 2.1 | 4.9 | −1.4 | 1.34E-07 |
| HLA-DPB1 | NM_002121 | 6p21.3 | 2.1 | 4.5 | −1.3 | 1.75E-07 |
| CD86 | NM_175862 | 3q21 | 2.1 | 2.9 | −1.3 | 1.03E-06 |
| C1QA | NM_015991 | 1p36.12 | 2.1 | 4.3 | −1.2 | 1.24E-07 |
| TLR7 | NM_016562 | Xp22.3 | 2.0 | 3.6 | −1.3 | 7E-08 |
| CCND1 | NM_053056 | 11q13 | 2.0 | 2.7 | −1.1 | 1.48E-11 |
| HLA-DQA1 | NM_002122 | 6p21.3 | 2.0 | 2.6 | −1.2 | 4.19E-05 |
| FAM105A | NM_019018 | 5p15.2 | 2.0 | 2.6 | −1.1 | 9.2E-08 |
| C6orf138 | NM_001013732 | 6p12.3 | 2.0 | 3.4 | −1.2 | 1.99E-10 |
| P2RY13 | NM_176894 | 3q24 | 2.0 | 2.4 | −1.2 | 3.08E-06 |
| PROS1 | NM_000313 | 3q11.2 | 2.0 | 5.0 | −1.4 | 9.1E-14 |
Official gene symbol is shown for every gene. C-M values correspond to the fold-change value of control healthy meninges (C) minus meningioma (M). In the case of N-S, N refers to nerve healthy tissue minus schwannoma (S). In the column M-S, meningioma (M) minus schwannoma (S) is performed. Only those genes with ≤1.5 fold-change between both tumors are shown.