Table II.
Genes infraexpressed in meningioma and schwannoma when compared with their respective control tissue.
| Gene | Database | Chromosome | C-M | N-S | M-S | P-value |
|---|---|---|---|---|---|---|
| SAA1 | NM_000331 | 11p15.1 | −2.0 | −2.7 | 1.1 | 0.000414 |
| INHBA | NM_002192 | 7p15-p13 | −2.0 | −4.1 | 1.2 | 2.42E-09 |
| PCDH18 | NM_019035 | 4q31 | −2.0 | −2.6 | 1.2 | 0.000183 |
| PTGIS | NM_000961 | 20q13.13 | −2.1 | −3.4 | 1.3 | 1.72E-06 |
| HHIP | NM_022475 | 4q28–q32 | −2.1 | −2.9 | 1.1 | 1.44E-06 |
| AQP9 | NM_020980 | 15q | −2.1 | −4.5 | 1.0 | 2.78E-08 |
| TCEAL2 | NM_080390 | Xq22.1–q22.3 | −2.1 | −2.4 | 1.4 | 0.000135 |
| S100A12 | NM_005621 | 1q21 | −2.2 | −5.6 | 1.1 | 9.51E-07 |
| PDE3A | NM_000921 | 12p12 | −2.2 | −2.0 | 1.2 | 2.03E-08 |
| S100A9 | NM_002965 | 1q21 | −2.2 | −4.6 | −1.0 | 2.63E-05 |
| PAK3 | NM_002578 | Xq23 | −2.3 | −4.1 | 1.3 | 5.36E-11 |
| SLC16A7 | NM_004731 | 12q13 | −2.3 | −2.2 | 1.1 | 4.89E-12 |
| PI16 | NM_153370 | 6p21.2 | −2.3 | −5.1 | 1.2 | 1.76E-09 |
| MGST1 | NM_145792 | 12p12.3-p12.1 | −2.3 | −3.6 | 1.1 | 0.001079 |
| FGFR2 | NM_000141 | 10q26 | −2.3 | −2.6 | 1.3 | 1.69E-09 |
| TRPM3 | NM_206946 | 9q21.12 | −2.4 | −2.0 | 1.1 | 3.65E-11 |
| PDZRN4 | NM_013377 | 12q12 | −2.5 | −3.0 | 1.1 | 1.14E-08 |
| THBS4 | NM_003248 | 5q13 | −2.5 | −3.5 | 1.0 | 1.71E-09 |
| STEAP4 | NM_024636 | 7q21.12 | −2.7 | −4.2 | 1.1 | 1.38E-07 |
| DCLK1 | NM_004734 | 13q13 | −2.8 | −2.4 | 1.1 | 2.22E-07 |
| ZNF385D | NM_024697 | 3p24.3 | −3.0 | −2.0 | 1.1 | 1.34E-05 |
| CXCL2 | NM_002089 | 4q21 | −3.1 | −3.3 | −1.0 | 7.52E-09 |
| FABP4 | NM_001442 | 8q21 | −3.1 | −13.5 | 1.2 | 1.29E-12 |
| IL6 | NM_000600 | 7p21 | −3.1 | −4.6 | −1.0 | 0.000397 |
| SELE | NM_000450 | 1q22–q25 | −3.3 | −6.6 | 1.0 | 2.29E-09 |
| SLC14A1 | NM_001128588 | 18q11–q12 | −4.0 | −3.3 | 1.0 | 2.7E-09 |
| APLNR | NM_005161 | 11q12 | −4.8 | −3.1 | −1.0 | 8.05E-11 |
| ADH1B | NM_000668 | 4q23 | −4.9 | −3.6 | −1.1 | 6.95E-07 |
| ADCYAP1R1 | NM_001118 | 7p14 | −5.1 | −3.3 | 1.0 | 6.98E-11 |
| RND1 | NM_014470 | 12q12 | −5.4 | −3.1 | −1.0 | 3.5E-09 |
| ADAMTS1 | NM_006988 | 21q21.2 | −6.0 | −2.4 | −1.1 | 4.64E-11 |
| HSPB8 | NM_014365 | 12q24.23 | −6.0 | −3.5 | 1.0 | 5.3E-07 |
| AOC3 | NM_003734 | 17q21 | −6.3 | −2.5 | −1.1 | 3.64E-11 |
| RGS4 | NM_001102445 | 1q23.3 | −6.7 | −2.1 | −1.1 | 2.55E-10 |
| STMN2 | NM_007029 | 8q21.13 | −9.2 | −2.9 | −1.1 | 4.92E-11 |
Official gene symbol is shown for every gene. C-M values correspond to the fold-change value of control healthy meninges (C) minus meningioma (M). In the case of N-S, N refers to nerve healthy tissue minus schwannoma (S). In the column M-S, meningioma (M) minus schwannoma (S) is performed. Only those genes with ≤1.5 fold-change between both tumors are shown.