Table 2.
Baseline Patient and Caregivers Characteristics by Caregiver Depression Trajectory Class
| Characteristic | Categories | Class 1: (n = 92) Stable caregivers |
Class 2: (n = 41) Wear-and-tear caregivers |
p-Value |
|---|---|---|---|---|
| Patient demographic and clinical characteristics | ||||
| Patient age | Mean ± SD | 75.2 | 76.78 | .25 |
| Patient gender |
Female Male |
63.04% 37.96% |
39.02% 60.98% |
.01 |
| Patient ethnicity | White | 90.22% | 90.44% | .99 |
| Site | Columbia University Johns Hopkins Mass General |
44.57% 23.91% 31.52% |
51.22% 19.51% 29.27% |
.76 |
| Diagnosis | Alzheimer’s disease dementia with Lewy Bodies |
85.87% 14.13% |
87.8% 12.2% |
.76 |
| Lives in nursing home | Yes | 31.9% | 17.1% | .09 |
| Neurologist estimation of duration of illness in years | Mean ± SD (range 1–18) | 7.57 (3.32) | 6.73 (2.7) | .17 |
| Modified Mini-mental state examination score at study baseline | Mean ± SD (range 9–30) | 17.59 | 19.06 | .34 |
| Blessed functional activity scale score at study baseline | Mean ± SD (range 0–13) | 6.95 | 7.41 | .53 |
| Presence of any behavioral symptom at baseline | Yes | 54.44% | 57.5% | .75 |
| Modified comorbidity index | 0 ≥ 1 | 51.14% 48.86 |
52.5% 47.5% |
.89 |
| Extrapyramidal signs | Yes | 14.44% | 12.5% | .77 |
| Caregiver characteristics and activities | ||||
| Caregiver age | Mean ± SD | 63.67 (13.35) |
68.65 (14.47) |
.06 |
| Caregiver gender | Female | 77.17% | 73.17% | .62 |
| Lives with patient | Yes | 54.35% | 70.73% | .08 |
| Relationship to patient | Spouse | 47.83% | 70.83% | .01 |
| Work at least part-time for pay | Yes | 51.25% | 33.33% | .07 |
| Home health aide in last 3 months | Yes | 23.46% | 31.58% | .35 |
| Time spent daily with patient |
None Up to 3 hours 3 to 5 hours 6 to 9 hours 9 to 12 hours More than 12 hours |
2.22% 35.56% 13.33% 12.22% 8.89% 27.78% |
2.44% 17.07% 9.76% 7.32% 4.88% 58.54% |
.04 |
| Assists patient with ADLs | Yes | 17.72% | 29.73% | .14 |
Note: SD = standard deviation; ADLs = Activities of daily living and include bathing, eating; IADLS = Instrumental activities of daily living and include shopping, housekeeping.