Figure 7. Modulatory effects of Withanolide A and β-Amyloid_1-42 on human neuronal cells.

A. Dose-response of Withanolide A showing growth-stimulatory effects in terms of % viability. B. MTT assay showing the inhibition of cell viability by β-Amyloid_1-42 and its reversal by Withanolide A at two concentrations on SK-N-MC cells. The values were expressed as percentage of cell viability compared to control cells and are the mean ± SD of four experiments. *** and ** indicates a statistically significant difference (p<0.0001) and (p<0.0018) respectively compared to controls. WA – Withanolide A; β-AMY - β-Amyloid_1-42