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. Author manuscript; available in PMC: 2014 Nov 21.
Published in final edited form as: Bioessays. 2010 Mar;32(3):197–206. doi: 10.1002/bies.200900114

Figure 2.

Figure 2

Spatial and temporal aspects of development of the laminar cortex. A: Schematic representation of the region of interest (boxed). B: In the dorsal telencephalon, neural progenitors in the VZ and later in the SVZ, give rise to PN, which migrate to their appropriate layers. PN subtypes are born in a temporally distinct manner, with the deeper layer neurons born early in development, and the upper layer neurons born later. Each cortical layer contains multiple types of PN that connect to different intracortical, subcortical, and subcerebral targets. CP, cortical plate; Ctx, cortex; IZ, intermediate zone; LGE, lateral ganglionic eminence; LV, lateral ventricle; MGE, medial ganglionic eminence; MZ, marginal zone; PP, preplate; SP, subplate; SVZ, subventricular zone; VZ, ventricular zone; WM, white matter.