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. 2014 Nov 21;9(11):e113600. doi: 10.1371/journal.pone.0113600

Figure 1. Non-Reducing SDS-PAGE analysis and schematic of FVIII variants.

Figure 1

(A) SC rFVIIIFc R1645A/R1648A, SC rFVIIIFc, fully processed rFVIIIFc and rFVIIIFc [10] were compared by non-reducing SDS-PAGE. (B) Schematic presentation of SC rFVIIIFc, fully processed rFVIIIFc, and the common thrombin-activated form.