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. 2014 Nov 21;9(11):e113600. doi: 10.1371/journal.pone.0113600

Figure 2. Thrombin generation profile of FVIII variants.

Figure 2

Activity determination was based on equal chromogenic activity. Representative curves with selected concentrations are shown in (A) 1 IU/mL (B) 0.25 IU/mL (C) 0.0625 IU/mL. Select parameters are shown in (D) as peak thrombin and (E) as ETP.