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. 2014 Nov 21;9(11):e113100. doi: 10.1371/journal.pone.0113100

Table 1. Comparison of human CD4 and CD8 T-lymphocyte epitope sequences between respiratory syncytial virus Memphis-37 and A2 strains.

RSV protein Amino acid position Peptide sequence* % Homology between peptides
RSV-Memphis-37 RSV-A2
CD4 G 162−175 DFHFEVFNFVPCSI DFHFEVFNFVPCSI 100
F 7−30 KTNAITTILAAVTLCFASSQNITE KANAITTILTAVTFCFASGQNITE 83
F 25−42 SQNITEEFYQSTCSAVSK GQNITEEFYQSTCSAVSK 94
F 43−60 GYLSALRTGWYTSVITIE GYLSALRTGWYTSVITIE 100
F 49−72 RTGWYTSVITIELSNIKENKCNGT RTGWYTSVITIELSNIKENKCNGT 100
F 55−72 SVITIELSNIKENKCNGT SVITIELSNIKENKCNGT 100
F 73−90 DAKVKLIKQELDKYKNAV DAKVKLIKQELDKYKNAV 100
F 85−102 KYKNAVTELQLLMQSTPA KYKNAVTELQLLMQSTPP 94
F 109−132 RELPRFMNYTLNNTKNNNVTLSKK RELPRFMNYTLNNAKKTNVTLSKK 88
F 175−192 NKAVVSLSNGVSVLTSKV NKAVVSLSNGVSVLTSKV 100
F 193−210 LDLKNYIDKQLLPIVNKQ LDLKNYIDKQLLPIVNKQ 100
F 229−252 RLLEITREFSVNAGVTTPVSTYML RLLEITREFSVNAGVTTPVSTYML 100
F 265−288 PITNDQKKLMSNNVQIVRQQSYSI PITNDQKKLMSNNVQIVRQQSYSI 100
F 295−318 EVLAYVVQLPLYGVIDTPCWKLHT EVLAYVVQLPLYGVIDTPCWKLHT 100
F 337−360 TDRGWYCDNAGSVSFFPQAETCKV TDRGWYCDNAGSVSFFPQAETCKV 100
F 391−408 YDCKIMTSKTDVSSSVIT YDCKIMTSKTDVSSSVIT 100
F 409−426 SLGAIVSCYGKTKCTASN SLGAIVSCYGKTKCTASN 100
F 427−444 KNRGIIKTFSNGCDYVSN KNRGIIKTFSNGCDYVSN 100
F 457−486 YYVNKQEGKSLYVKGEPIINFYDPLVFPSD YYVNKQEGKSLYVKGEPIINFYDPLVFPSD 100
F 493−516 SQVNEKINQSLAFIRKSDELLHNV SQVNEKINQSLAFIRKSDELLHNV 100
F 517−534 NVGKSTTNIMITTIIIVI NAGKSTTNIMITTIIIVI 94
F 541−558 LIAVGLFLYCKARSTPVT LIAVGLLLYCKARSTPVT 94
CD8 F 8−17 TNAITTILAA ANAITTILTA 80
F 93−102 LQLLMQSTPA LQLLMQSTPA 100
F 106–113 RARRELPRF RARRELPRF 100
F 109–118 RELPRFMNYT RELPRFMNYT 100
F 260–269 LINDMPITND LINDMPITND 100
F 273–282 LMSNNVQIVR LMSNNVQIVR 100
F 285–294 SYSIMSIIKE SYSIMSIIKE 100
F 374–383 TLPSEVNLCN TLPSEVNLCN 100
F 388–397 NPKYDCKIMT NPKYDCKIMT 100
F 519–528 GKSTTNIMIT GKSTINIMIT 90
F 521–530 STTNIMITTI STINIMITTI 90
F 542–550 IAVGLFLYC IAVGLLLYC 89
N 46–59 KLCGMLLITEDANH KLCGMLLITEDANH 100
N 232–245 STRGGSRVEGIFAG STRGGSRVEGIFAG 100
N 250–263 AYGAGQVMLRWGVL AYGAGQVMLRWGVL 100
N 253–266 AGQVMLRWGVLAKS AGQVMLRWGVLAKS 100
N 256–269 VMLRWGVLAKSVKN VMLRWGVLAKSVKN 100
N 298–311 AGFYHILNNPKASL AGFYHILNNPKASL 100
N 306–314 NPKASLLSL NPKASLLSL 100
M 195–203 IPYSGLLLV IPYSGLLLV 100
M 229–237 YLEKESIYY YLEKESIYY 100
M2-1 64–72 AELDRTEEY AELDRTEEY 100
M2-1 151–159 RLPADVLKK RLPADVLKK 100
NS1 41–49 LAKAVIHTI LAKAVIHTI 100

Legend: *Differences between Memphis-37 and RSV A2 are bolded.