Table 4.

Multivariate RS expressions of bone maturation improve classification accuracy over common peak ratios.

Rotation	SMLR input	Value ($\text{mean}\pm \mathrm{STDEV}$) 8 week	Value ($\text{mean}\pm \mathrm{STDEV}$) 20 week	Genotype separationa$P_{\text{value}}$ %	Correctly classified	Specificity (%)	Sensitivity (%)
–	$\mu \mathrm{CT}$ TMD	$1147\pm 33.42$	$1263\pm 21.57$	$p<0.0001$	18/33	0	100
O	MCR (ν1/AmI)	$11.27\pm 1.741$	$11.45\pm 2.876$	NS	18/33	0	100
L	MCR (ν1/AmI)	$16.3\pm 2.712$	$16.33\pm 3.147$	NS	18/33	0	100
O	Carb sub	$0.1457\pm 0.0056$	$0.1568\pm 0.0061$	$p<0.0001$	15/33	0	100
L	Carb sub	$0.1445\pm 0.0045$	$0.1552\pm 0.0064$	$p<0.0001$	15/33	0	100
O	Crystallinity	$0.0642\pm 0.0006$	$0.0649\pm 0.0008$	$p=0.0094$	18/33	0	100
L	Crystallinity	$0.064\pm 0.0007$	$0.0646\pm 0.0009$	NS	18/33	0	100
O	PC4 score	$4.174\pm 5.921$	$-5.008\pm 9.431$	$p=0.004$	29/33	87	89
L	PC5 score	$3.076\pm 4.628$	$-3.691\pm 6.797$	$p=0.003$	28/33	87	83
[O, L]	PC3 score	$7.47\pm 15.09$	$-8.964\pm 15.75$	$p=0.0007$	28/33	73	94

^aAge difference is determined by Mann Whitney U test, significance at $p<0.05$