Table 2.
Clinical outcomes
| Study number |
Ureaplasma culture status |
Status @ 36 wk PMA |
Timed O2 reduction test performed |
Results of Timed O2 reduction test |
Physiologic BPD @ 36 wk PMA |
|---|---|---|---|---|---|
| 1 | Pos | Died 56 d | |||
| 2 | Pos | Alive, SIMV |
No | Yes | |
| 3 | Pos | Alive, NC | Yes | Passed | No |
| 4 | Pos | Died 21 d | |||
| 5* | Pos | Alive, nCPAP |
No | Yes | |
| 6 | Pos | Alive, NC | Yes | Passed | No |
| 7 | Pos | Alive, SIMV |
No | Yes | |
| 8** | Pos | Died 3 d | |||
|
All positives |
3 deaths | 2/5 | 2 | 3/5 (60%) | |
| 9 | Neg | Alive, NC | Yes | Passed | No |
| 10 | Neg | Alive, NC | Yes | Passed | No |
| 11 | Neg | Alive, NC | Yes | Passed | No |
| 12 | Neg | Transferred, NC |
No | Yes | |
| 13 | Neg | Alive, room air |
No | No | |
| 14 | Neg | Alive, NC | Yes | Passed | No |
|
All negatives |
0 deaths | 4/6 | 4 | 1/6 (17%) | |
| Total | 3 deaths | 6 | 6 | 4/14 (29%) | |
received 2 additional doses azithromycin (protocol violation);
withdrawn prior to dosing due to clinical deterioration
PMA: post-menstrual age
NC: nasal cannula; nCPAP: nasal continuous positive pressure; SIMV: synchronized intermittent mandatory ventilation