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Population pharmacokinetic parameter estimates for azithromycin in preterm neonates
| Parameter | Estimate (% RSE) | % ISV (%RSE) |
|---|---|---|
| CL (L/h) | 0.18 x WT0.75 (8.2) | 23.5 (44.6) |
| V1 (L) | 0.93 (12.1) | NE |
| Q (L/h) | 1.0 (13.2) | NE |
| V2 (L) | 14.2 x WT (9.2) | 26.2 (50.6) |
| Residual Error (%) | 28.7 (15.0) | --- |
RSE: relative standard error
ISV: intersubject variability, calculated as the square root of the estimated variance of intersubject variability (i.e., ω) x100
WT: body weight in kilograms
NE: not estimated
