Table 4.
Tracheal aspirate cytokine concentrations pre- and post-azithromycin therapy*
| Cytokine | Pre-dose (N=12) |
D2 post-dose (N=9) |
|---|---|---|
| IL-6 (pg/mL) | 204 (92–444) |
148 (67–255) |
| IL-6 Ureaplasma positive | 237 (128–400) |
147 (67–255) |
| IL-6 Ureaplasma negative | 107 (76–1070) |
148 (64–721) |
| IL-8 (pg/mL) | 4560 (1980–6595) |
2910 (2250–5850) |
| IL-8 Ureaplasma positive | 5850 (2140–-5850) |
3110 (2220–5850) |
| IL-8 Ureaplasma negative | 2700 (1820–14200) |
2750 (2250–8170) |
| IL-1β (pg/mL) | 20.14 (2–89) |
40.4 (25–91) |
| IL-1β Ureaplasma positive | 24 (2–95) |
63 (25–599) |
| IL-1β Ureaplasma negative | 4 (2–82) |
30 (5–91) |
| MPO (units/mg protein) | 0.6 (0.3–1.5) |
0.5 (0.3–0.8) |
| MPO Ureaplasma positive | 0.6 (0.3–2.0) |
1.2 (0.2–3.0) |
| MPO Ureaplasma negative | 0.5 (0.3–1.2) |
0.5 (0.1–0.8) |
*
Data are expressed as median with 25th to 75th percentiles in parentheses