. Author manuscript; available in PMC: 2015 Oct 1.

Published in final edited form as: Eur J Pharm Biopharm. 2014 May 21;88(2):332–341. doi: 10.1016/j.ejpb.2014.05.012

Table 4.

Correlation coefficients R from linear regression plots of the fraction of KGF-2 that aggregated (top) or oxidized (bottom) in disaccharide and disaccharide:HES formulations during 16 weeks of storage, vs. formulation glass transition temperature, increase in infrared peak width, ln(τ^β), and inverse mean square displacement of hydrogen atoms.

Storage Temperature	R², Fraction KGF-2 Aggregated vs. Tg	R², Fraction KGF-2 Aggregated vs. ΔW_1/2	R², Fraction KGF-2 Aggregated vs. ln(τ^β)	R², Fraction KGF-2 Aggregated vs. <u²>⁻¹
40 °C	.78	.70	.34	.72
50 °C	.72	.62	.24	.74
60 °C	.77	.69	.28	.65

Storage Temperature	R², Fraction KGF-2 Oxidized vs. Tg	R², Fraction KGF-2 Oxidized vs. ΔW_1/2	R², Fraction KGF-2 Oxidized vs. ln(τ^β)	R², Fraction KGF-2 Oxidized vs. <u²>⁻¹
40 °C	.89	.86	.58	.49
50 °C	.68	.61	.33	.75
60 °C	.20	.15	.00	.50