Table 3.
Distribution of Q223R genotypes in relation to breast cancer risk (Unconditional logistic regression)
| Genotype | Breast cancer cases | Controls | OR ( 95%CI) | P-value |
|---|---|---|---|---|
|
| ||||
| 25 (25.0) | 54 (54.0) | 1.0 | ||
| QR | 56 (56.0) | 40 (40.0) | 3.02 (1.62-5.64) | 0.001 |
| RR | 19 (19.0) | 6 (6.0) | 6.84 (2.43-19.21) | <0.001 |
| 25 (25.0) | 54 (54.0) | 1.0 | ||
| QR+RR | 75 (75.0) | 56 (56.0 ) | 3.52 (1.93-6.41) | <0.001 |
Data are presented as number of cases with frequency in parentheses
Results were presented for the dominant genetic model (homozygous for LEPR 223 QQ vs. Carriers of R allele). OR: odds ratio; CI: confidence interval