Table 3. Risk factors for attrition and mortality of patients starting ART in Karonga District, 2005-2012*.
Attrition | Mortality | |||||
---|---|---|---|---|---|---|
| ||||||
Risk factor | Unadjusted HR (95% CI) | Adjusted HR (95% CI) | P-value | Unadjusted HR (95% CI) | Adjusted HR (95% CI) | P-value |
Age | <0.001 | NS | ||||
15-34 years | 1.24 (1.12-1.37) | 1.32 (1.19-1.46) | 1.05 (0.91-1.21) | 1.12 (0.97-1.29) | ||
≥35 years | 1 | 1 | 1 | 1 | ||
Gender | <0.001 | <0.001 | ||||
Male | 1.39 (1.26-1.54) | 1.49 (1.34-1.65) | 1.54 (1.34-1.77) | 1.61 (1.39-1.85) | ||
Female | 1 | 1 | 1 | 1 | ||
Distance from clinic | NS | NS | ||||
<5km | 1 | 1 | 1 | 1 | ||
5 - <10km | 0.95 (0.83-1.08) | 1.04 (0.91-1.20) | 0.85 (0.70-1.04) | 0.98 (0.80-1.19) | ||
10 - <25km | 1.09 (0.96-1.24) | 1.05 (0.92-1.19) | 1.13 (0.94-1.35) | 1.04 (0.86-1.24) | ||
≥25km | 1.64 (1.40-1.92) | 1.04 (0.88-1.23) | 1.95 (1.58-2.41) | 0.98 (0.79-1.22) | ||
Reason for starting ART | <0.001 | <0.001 | ||||
CD4 cell count criteria | 1 | 1 | 1 | 1 | ||
WHO stage 3 | 1.91 (1.56-2.35) | 1.60 (1.30-1.97) | 2.23 (1.60-3.12) | 1.69 (1.20-2.37) | ||
WHO stage 4 | 3.98 (3.23-4.91) | 2.51 (2.02-3.13) | 6.65 (4.76-9.27) | 3.27 (2.31-4.63) | ||
Year of ART initiation | <0.001 | <0.001 | ||||
Per increasing calendar year | 0.77 (0.75-0.79) | 0.82 (0.79-0.84) | 0.68 (0.66-0.71) | 0.74 (0.71-0.77) |
Complete data for 8,116 patients.
HR: Hazard Ratio; CI: Confidence Interval; NS: non-significant