Table 4.
The association between serum uric acid level and all-cause or cardiovascular mortality in men.
| Seum uric acid, mg/dL |
Number Of Subjects |
Person- years |
Deaths | Mortality per 1000 person- years |
Age- Adjusted hazard ratio (95% CI) |
Model D multivariate hazard ratio (95% CI) |
|---|---|---|---|---|---|---|
| All cause mortality | ||||||
| 0–5.2 | 708 | 9404 | 194 | 20.6 | 1 | 1 |
| >5.2–6.0 | 710 | 9602 | 165 | 17.2 | 0.88 (0.62–1.23) | 0.93 (0.64–1.36) |
| >6.0–6.9 | 626 | 8456 | 148 | 17.5 | 0.80 (0.59–1.07) | 0.79 (0.56–1.11) |
| >6.9 | 675 | 8731 | 189 | 21.6 | 1.01 (0.68–1.48) | 0.97 (0.60–1.57) |
| Serum uric acid: comparing persons with a serum UA difference of 1 | N/A | N/A | N/A | N/A | 0.99 (0.88–1.11) | 0.97 (0.85–1.10) |
| Cardiovascular mortality | ||||||
| 0–5.2 | 708 | 9404 | 63 | 6.7 | 1 | 1 |
| >5.2–6.0 | 710 | 9602 | 65 | 6.8 | 1.24 (0.68–2.25) | 1.63 (0.94–2.82) |
| >6.0–6.9 | 626 | 8456 | 49 | 5.8 | 0.68 (0.44–1.08) | 0.72 (0.42–1.24) |
| >6.9 | 675 | 8731 | 67 | 7.7 | 0.98 (0.50–1.92) | 0.92 (0.49–1.71) |
| Serum uric acid: comparing persons with a serum UA difference of 1 | N/A | N/A | N/A | N/A | 0.95 (0.77–1.17) | 0.94 (0.80–1.10) |
*
Adjusted for age, race/ethnicity, smoking, alcohol consumption, educational attainment, physical activity, body mass index, waist-to-hip ratio, serum C-reactive protein, plasma triglyceride, total cholesterol, and HDL cholesterol, use of aspirin, NSAIDs, and diuretics and coffee, meat, fish, dairy, and sugar-sweetened beverage consumption, diabetes, insulin resistance, systolic blood pressure, diastolic blood pressure, use of antihypertensives, glomerular filtration rate and urine albumin-creatinine ratio.