Table 1.
Parameter | Mean ± SEM | Median | Range | |
---|---|---|---|---|
Depth (μm) | 779 ± 31 | 760 | 510–1170 | |
Spontaneous activity (spikes s−1) | 2.9 ± 0.5 | 2.0 | 0–15.0 | |
Thermal stimulation | ||||
A-nociceptor activation | Overall response (spikes per ramp s−1) | 24.7 ± 2.3 | 24.1 | 4.5–56.2 |
Firing threshold (°C) | 44.8 ± 0.5 | 44.6 | 38.0–50.4 | |
Suprathreshold activity (spikes s−1) | 40.0 ± 2.3 | 39.7 | 13.4–78.2 | |
C-nociceptor activation | Overall response (spikes per ramp s−1) | 14.3 ± 2.0 | 10.9 | 0.4–34.1 |
Firing threshold (°C) | 42.6 ± 0.8 | 41.7 | 36.9–52.5 | |
Suprathreshold activity (spikes s−1) | 21.8 ± 1.4 | 21.3 | 3.8–38.3 | |
Electrical stimulation | A-fibre threshold (V) | 1.7 ± 0.1 | 2.0 | 0.5–3.0 |
C-fibre threshold (C+ve cells only, n = 26; V) | 11.1 ± 0.9 | 10.5 | 6.0–25.0 | |
Spikes at C-fibre latency at 1.5 T (C+ve cells only, n = 26) | 4.6 ± 0.6 | 3.7 | 0.9–10.9 | |
Spikes at C-fibre latency at 3 T (C+ve cells only, n = 26) | 6.7 ± 0.8 | 4.9 | 2.1–15.1 |
The data show the depth of neurons (n = 27) from the cord surface, level of spontaneous activity and response properties to electrical and thermal stimulation of recorded units.