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. 2014 Aug 14;19(11):1310–1320. doi: 10.1111/tmi.12368

Table 4.

Prevalence of TF and mortality by pneumonia severity classification

Pneumonia severity classification TF 1 – a priori definition Frequency (%, 95% CI) TF 2 – Alternative definition Frequency (%, 95% CI) N
All SP 21 (12.4, 7.9–18.4) 3 (1.8, 0.4–5.1) 169
 SP/benzyl penicillin (group I) 17* (17.2, 10.3–26.1) 2 (2.0, 0.3–7.1) 99
 SP/benzyl penicillin and gentamicin/other antibiotics (group II) 4 (5.7, 1.6–14.0) 1 (1.4, 0.04–7.7) 70
All VSP 79 (39.3, 32.5–46.4) 43 (21.4, 15.9–27.7) 201
 VSP/benzyl penicillin and gentamicin (group III) 56 (41.8, 33.3–50.6) 28 (20.9, 14.4–28.8) 134
 VSP/benzyl penicillin (group IV) 5 (15.2, 5.1–31.9) 1 (3.0, 0.1–15.8) 33
 VSP/other antibiotics (group V) 18§ (52.9, 35.1–70.2) 14 (41.2, 24.6–59.3) 34
Total 100 (27.0, 22.6–31.9) 46 (12.4, 9.2–16.2) 370

SP, severe pneumonia; TF, treatment failure; VSP, very severe pneumonia.

*

Two deaths.

14 deaths.

One death.

§

Six deaths.