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. 2014 Nov 6;2014:130359. doi: 10.1155/2014/130359

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Copyright © 2014 Marianna Tyczewska et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Affymetrix Rat Gene 1.1 ST Array. Ontology analyses of up-/downregulated genes (fold >2, P < 0.05) using GeneAnswer (part of the R project) based on Gene Ontology database. On the left side functional categories were placed, on the bottom of the graph—total number of genes up-/downregulated during adrenal regeneration. Genes with changed expression (fold >2, P < 0.05) compared to control were grouped in functional categories. In each category hypergeometric statistical test was performed. Green color—statistically significant changes of expression (P < 0.05). If P value is lower, green color is more intense. It should be emphasized that GO database is composed of some general as well as specific categories with similar meanings and therefore a single gene may be mapped to several GO terms and may be counted more than ones.