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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Exp Neurol. 2014 Feb 6;254:180–189. doi: 10.1016/j.expneurol.2014.01.020

Figure 7.

Figure 7

SN79 (3 mg/kg × 4) treatment attenuates METH-induced (5 mg/kg × 4) neuronal degeneration in the striatum as measured by Fluoro-Jade B staining. (A) Representative images of Fluoro-Jade B labeled degenerating neurons in the striatum for each respective treatment group. Clockwise from top left: Sal/Sal, Sal/METH, SN79/METH, SN79/Sal. (B) Quantification of striatal neuronal degeneration by treatment group. One-way ANOVA, followed by post hoc Tukey's multiple comparison tests. n=5/group, 3 slices/brain averaged for each data point. ***p < 0.001, Sal/METH vs. Sal/Sal; ##p < 0.01, SN79/METH vs. Sal/METH