Zone 1 |
Fibroblasts |
Linearly arranged collagen with mechanical properties similar to mid-substance tendon (1,8,10,11) |
Pure Dense Fibrous |
Type I Collagen |
Connective Tissue |
Type III Collagen (1,8,10,11) |
|
Zone 2 |
Fibrochondrocytes |
Dissipates bending of collagen fibers in tendon (2) |
Uncalcified Fibrocartilage |
Proteoglycan aggrecan with Collagen (Types I–III) (1,2,8,10–14) |
|
|
Tidemark |
|
Basophilic demarcation between uncalcified and calcified fibrocartilage representing the boundary between soft and hard tissues (8) |
|
Zone 3 |
Fibrochondrocytes |
Irregularity of attachments into bone give mechanical integrity of enthesis (2) |
Calcified Fibrocartilage |
Type II Collagen (Predominant) |
|
Type I Collagen |
|
Type X Collagen (1,2,3,10–14) |
|
Zone 4 |
Osteocytes |
Provides sites of attachment for the tendon |
Bone |
Osteoblasts |
|
|
Osteoclasts (1,8) |
|
|
Type I Collagen |
|