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. 2014 Nov 17;4(3):333–342.

Table 2.

Zones of fibrocartilaginous entheses.

Composition Significance
Zone 1 Fibroblasts Linearly arranged collagen with mechanical properties similar to mid-substance tendon (1,8,10,11)
Pure Dense Fibrous Type I Collagen
Connective Tissue Type III Collagen (1,8,10,11)

Zone 2 Fibrochondrocytes Dissipates bending of collagen fibers in tendon (2)
Uncalcified Fibrocartilage Proteoglycan aggrecan with Collagen (Types I–III) (1,2,8,10–14)

Tidemark Basophilic demarcation between uncalcified and calcified fibrocartilage representing the boundary between soft and hard tissues (8)

Zone 3 Fibrochondrocytes Irregularity of attachments into bone give mechanical integrity of enthesis (2)
Calcified Fibrocartilage Type II Collagen (Predominant)
Type I Collagen
Type X Collagen (1,2,3,10–14)

Zone 4 Osteocytes Provides sites of attachment for the tendon
Bone Osteoblasts
Osteoclasts (1,8)
Type I Collagen