Figure 3.

Comparison of raw moments obtained from stochastic simulations (left column) and from the TME model (right column) as functions of parameter ρ, and for various values of δ. (A) Average gene activity 〈G〉. (B and C) Second raw moments 〈GM〉 and 〈P²〉. (D and E) Third raw moments 〈GUP〉 and 〈GP²〉. Curves for different values of δ are color-coded according to legend box. The value of Λ = 100 used in the simulations corresponds to strong feedback (strong gene repression). Stochastic simulations are performed while constraining k_off/k_on = 100 and β/δ_p = 10 (see Methods for details). To see this figure in color, go online.