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. Author manuscript; available in PMC: 2014 Nov 24.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Aug 4;(8):CD007701. doi: 10.1002/14651858.CD007701.pub2
Methods RCT.
Participants Setting: 102 women in a Cairo hospital, Egypt.
Inclusion criteria: women at term (> 37 weeks’ gestation) scheduled for induction, singleton viable fetus, intact membranes, no uterine contractions
Exclusion criteria: malpresentation, placenta previa, previous uterine surgery, contraindications to induction
Interventions Intervention group: self-administered IMN, 40 mg, 3 doses 12 hrs apart (scheduled for 36, 24 and 12 hrs before induction
Comparison group: placebo same regiment as intervention group
Outcomes CS, further induction agents required, PPH, Apgar score >7 at 5mins, NICU admission, side effects
Notes
Risk of bias
Item Authors’ judgement Description
Adequate sequence generation? Yes Computer generated sequence.
Allocation concealment? Yes Coded treatment packs prepared by pharmacy.
Blinding?
Women
Yes Placebo controlled trial.
Blinding?
Clinical staff
Yes
Incomplete outcome data addressed?
All outcomes
Yes All women randomised appear to be accounted for in the analysis