Methods	RCT, 2-arm trial.
Participants	Setting: not clear. 68 women included, Inclusion criteria: women with “well-dated” pregnancies with gestational age > 40 weeks and Bishop score < 9 Exclusion criteria: current indication for IOL, malpresentation, multiple pregnancy, previous CS, oligohydramnios (AFI < 5 cm). any contraindication to a trial of labour, current regular contractions
Interventions	All women were assessed prior to randomisation. Intervention group: vaginal misoprostol 25 mcg. Comparison group: placebo gel. Fetal and uterine monitoring for 1 hr after treatment then women were discharged home. Labour was induced if BIshop score > 8 after 41 weeks or all women after 42 weeks
Outcomes	Uterine hyperstimulation, mode of delivery, epidural, Apgar score, NICU admission. (Women with PROM were given oxytocin to “stimulate labour” but were not included as inductions in the analyses.)
Notes
Risk of bias
Item	Authors’ judgement	Description
Adequate sequence generation?	Yes	Computer generated sequence performed in hospital pharmacy.
Allocation concealment?	Yes	Placebo controlled trial.
Blinding? Women	Yes	Placebo of similar appearance.
Blinding? Clinical staff	Yes
Incomplete outcome data addressed? All outcomes	Yes	68 women were randomised, 4 were excluded after randomisation and did not receive the study medication, but were included in an ITT analysis
Free of other bias?	Unclear	No baseline imbalance apparent.