Figure 2.

Effect of oral administration of SLEE on carrageenan-induced paw oedema in mice. Animals received SLEE (30, 100, or 300 mg/kg, p.o.) or vehicle or dexamethasone (DEXA, 1 mg/kg, s.c.) and after 1 h an intraplantar injection of carrageenan (300 μg/paw). Graphics (a), (b), (c), and (d) represent the evaluation of paw oedema after 0.5, 1, 2, and 4 h, respectively, after carrageenan injection. Each bar represents the mean ± SEM of 5 animals. ^* P < 0.05, ^** P < 0.01 when compared with the control-treated group. Differences between groups were analyzed by analysis of variance (one-way ANOVA) followed by the Newman-Keuls test.