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Immune monitoring summary and clinical outcomes of patients who produced a measureable immune response.
| Arm | Patient No. | Increase in gp100 Tetramer-reactive Cells | Increase in CD8+ IFN-γ+ Cells | Clinical Status1 |
|---|---|---|---|---|
| Intramuscular | 17 | + | POD | |
| 25 | gp100280-288 + | POD | ||
| Particle-Mediated Epidermal Delivery | 4 | + | POD | |
| 5 | gp100280-288 + | NED | ||
| 9 | gp100209-217 +; gp100280-288 + | POD | ||
| 11 | + | POD | ||
| 22 | + | NED | ||
| 27 | gp100280-288 + | + | NED |
Abbreviations: NED, no evidence of disease; POD, progression of disease.
