Table 1.
Baseline patient characteristics and co-morbidities: Data shown as mean ± standard deviation or percentage.
| Alcohol Abuse | No Alcohol Abuse | p-value | |
|---|---|---|---|
| Total Number Patients | 13 | 22 | |
| Demographics and Co-morbidities | |||
| % Male | 77% | 41% | 0.07 |
| Enrollment Actual Body Wt (kg) | 77.8 ± 14.7 | 86.4 ± 22.0 | 0.22 |
| Height (cm) | 176.9 ± 9.0 | 171.5 ± 10.9 | 0.14 |
| Predicted Body Weight (kg) | 71.3 ± 9.9 | 64.7 ± 11.7 | 0.10 |
| Enrollment BSA | 1.9 ± 0.2 | 2.0 ± 0.2 | NS |
| Age | 50.6 ± 11.0 | 44.2 ± 15.3 | 0.19 |
| Race (%African American) | 77% | 86% | NS |
| Chronic Heart Disease | 0% | 14% | NS |
| Hx Pulmonary Disease | 8% | 27% | NS |
| Hx Renal Disease | 0% | 0% | NS |
| Hx Hepatic Disease | 23% | 5% | 0.13 |
| Hx HIV | 46% | 32% | NS |
| Smoker | 90% | 69% | NS |
| AUDIT Score | 18.1 | 0.3 | <0.0001 |
| SMAST Score | 6.2 | 0.3 | <0.0001 |
| Characteristics at Enrollment | |||
| APACHE II Score | 25.5 ± 7.3 | 23.8 ± 1.2 | NS |
| Lung Injury Score | 2.8 ± 0.6 | 2.8 ± 0.6 | NS |
| SOFA Score | 10.7 ± 6.8 | 11.1 ± 2.3 | NS |
| Creatinine | 1.3 ± 1.0 | 1.6 ± 1.1 | NS |
| Albumin | 1.5 ± 0.3 | 2.1 ± 0.6 | 0.005 |
| Primary ARDS Risk Factor | |||
| Sepsis | 77% | 77% | NS |
| Aspiration | 8% | 23% | NS |
| Trauma | 8% | 0% | NS |
| Pancreatitis | 8% | 0% | NS |
| Direct Lung Injury | 54% | 55% | NS |
BSA: Body Surface Area; AUDIT: Alcohol Use Disorder Identification Test; SMAST: Short Michigan Alcohol Screening Test; SOFA: Sequential Organ Failure Assessment; HIV: Human Immunodeficiency Virus