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Representative vascular architecture (CD34 stain) of nonfunctioning (a), prolactin-secreting (b), GH-secreting (c), and ACTH-secreting (d) macroadenomas. Vessel diameter is larger in prolactin- and ACTH-secreting adenomas than nonfunctioning and GH-secreting adenomas. Vessel density and area are lower in ACTH-secreting adenoma than nonfunctioning and PRL-secreting adenomas. Original magnification: 200x. Bar 100 μm.
