Table 2.

Biomedical applications of P(3HB) with different molecular weights

	Applications	P(3HB) MW (kDa)	Preparation procedure	Reference
P(3HB) LMW	Osteoblast scaffolds	220	P3HB and hydroxyapatite were mixed using mechanical and physical methods	Shishatskaya et al., 2006
	Scaffolds	89–110	Blends of P3HB and chitosan at different ratios were evaluated	Medvecky et al., 2014
	Nanofibrous scaffolds for bone tissue engineering	144	Electrospinning/electrospraying, P3HB and hydroxyapatite	Ramier et al., 2014
P(3HB)	Nanoparticles for retinoic acid (RA) delivery	350	50 nm particles of P3HB/RA were prepared by dialysis	Errico et al., 2009
	Microcapsules for drugs delivery	300	Microcapsules of 0.5–1.5 μm with P3HB and smectite clays were formed	da Silva-Valenzuela et al., 2010
	Scaffolds of PHB and otholits (osteoinductor) for bone tissue regeneration	300	Solutions of P3HB and otholits (1% w/w) were electrospinning	Filho et al., 2013
	Scaffolds 3D for osteoblasts engineering	524	P3HB and chitosan blends were evaluated	Mendonca et al., 2013
	Scaffolds for tissue engineering	300	P3HB scaffolds were prepared by salt leaching and electrospinning	Masaeli et al., 2012
	Nanofibrous scaffolds nerve tissue engineering	437	Blends of P3HB (50)/PHBV (50) were treated by electrospinning	Masaeli et al., 2013
P(3HB) UHMW	Scaffolds for tissue engineering	890	Chitosan and P3HB films were prepared by emulsion blending	Cao et al., 2005
	Scaffolds for nerve cells	1143	P3HB was treated with PEG reducing 10 fold-times its MW but promote cell growth	Chan et al., 2014