Figure 2.

This is an example of an intermediate-risk case with L-sided Gleason score 7 disease present. Note the asymmetric GTV to PTV expansion margins (L Panel) (2 mm around the R lobe versus 5 mm around the L lobe) to more widely encompass the possibility of significant extracapsular extension on the side with the higher Gleason score. This creates wider prescription (yellow line) isodose coverage on the higher-risk side, and also tends to create larger volumes of dose escalation within the prostate on the more heavily involved side (center panel). Finally, note full prescription isodose coverage (yellow line) encompassing at least 1 cm of adjacent seminal vesicle on the sagittal image, required for intermediate-risk cases only (SV/prostate junction denoted by the oblique black line)(R panel).