Fig. 6.

Tumor growth inhibition by PTX013 in the B16F10 melanoma model using different treatment schedules. a The effect of different scheduling of PTX013 while maintaining the same accumulative total treatment dose. All groups received a total of 20 mg/kg PTX013 at the end of the treatment span of 10 days. However, the groups were divided to receive either 10 injections of 2 mg/kg every day (q1dx10), 4 injections of 5 mg/kg every 3 days (q3dx4), or 2 injections of 10 mg/kg every 5 days (q5dx2). b Body weights of the mice during different treatment schedules of PTX013. Data points represent means ±SEM (n=10 each group)