Table 2.

Differential diagnosis table of neuroimaging features of Oculocerebrorenal syndrome of Lowe (OCRL).

	Cloacal Exstrophy	Bladder Exstrophy	Omphalocele	Gastroschisis
X-ray	Markedly wide pubic diastasis. Markedly increased iliac wing angle.	Wide pubic diastasis. Increased iliac wing angle.	N/A	N/A
US	Possible hydronephrosis due to VUR.	Possible hydronephrosis due to VUR.	N/A	N/A
CT	Exposed bladder plate and gut. GU and GI abnormalities. Neurospinal defects.	Exposed bladder plate. GU and GI abnormalities.	Extruded gut	Extruded gut
MRI (T1)	GU and GI abnormalities. Neurospinal defects. Abnormal pelvic floor musculature.	GU Abnormalities. Abnormal pelvic floor musculature.	N/A	N/A
MRI (T2)	GU and GI abnormalities. Neurospinal defects. Abnormal pelvic floor musculature.	GU Abnormalities. Abnormal pelvic floor musculature.	N/A	N/A
Pattern of Contrast Enhancement	Contrast is not necessary in the evaluation of this congenital anomaly.	Contrast is not necessary in the evaluation of this congenital anomaly.	Contrast is not necessary.	Contrast is not necessary in the evaluation of this congenital anomaly.

Abbreviations: (CBC) Complete Blood Count; (FLAIR) Fluid attenuated inversion recovery; (CK) creatine kinase; (NAA) N-acetyl aspartate; (VLCFA) very long chain fatty acid