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K. pneumonia ATCC 13883 susceptibility to polymyxin B and colistin and half maximal effective concentration (EC50) of polymyxins required to produce permeabilization of the outer membrane to NPN.
| Polymyxin B |
Colistin |
|||
|---|---|---|---|---|
| Strain | MIC (mg/l) |
NPN EC50
(μM) |
MIC (mg/l) |
NPN EC50
(μM) |
| Wild type | 0.5 | 0.58 ± 0.12 | 1 | 1.1 ± 0.32 |
| Resistant | 32 | ND | 32 | ND |
ND: not determined.
