TABLE 1.
Non-synonymous mutations of the human S1PR1 gene found in the NHLBI GO ESP database
| SNP Position | Identification Number (rs) | Alleles | EA Allele Number | AA Allele Number | Total Allele Number | cDNA Position | Protein Position | Amino Acid |
| 1:101704572 | rs61734752 | A/C | A = 1/C = 7,019 (0.014%) | A = 163/C = 3,575 (4.36%) | A = 164/C = 10,594 (1.52%) | 32 | 11 | Asp/Ala |
| 1:101704577 | rs41287280 | G/C | G = 116/C = 6,904 (1.65%) | G = 17/C = 3,721 (0.45%) | G = 133/C = 10,625 (1.24%) | 37 | 13 | Gly/Arg |
| 1:101704655 | rs140298731 | A/G | A = 0/G = 7,020 (0%) | A = 1/G = 3,737 (0.027%) | A = 1/G = 10,757 (0.0092%) | 115 | 39 | Thr/Ala |
| 1:101704674 | rs148977042 | C/T | C = 2/T = 7,018 (0.028%) | C = 2/T = 3,736 (0.054%) | C = 4/T = 10,754 (0.037%) | 134 | 45 | Thr/Ile |
| 1:101704775 | rs370003570 | T/C | T = 0/C = 7,020 (0%) | T = 1/C = 3,737 (0.027%) | T = 1/C = 10,757 (0.0092%) | 235 | 79 | Ser/Pro |
| 1:101704899 | rs149198314 | C/G | C = 1/G = 7,019 (0.014%) | C = 0/G = 3,738 (0%) | C = 1/G = 10,757 (0.0092%) | 359 | 120 | Pro/Arg |
| 1:101705133 | rs370425078 | G/A | G = 0/A = 7,020 (0%) | G = 1/A = 3,737 (0.027%) | G = 1/A = 10,757 (0.0092%) | 593 | 198 | Cys/Tyr |
| 1:101705252 | rs149041375 | T/C | T = 2/C = 7,018 (0.028%) | T = 1/C = 3,737 (0.027%) | T = 3/C = 10,755 (0.028%) | 712 | 238 | Cys/Arg |
| 1:101705274 | rs151135641 | A/G | A = 0/G = 7,020 (0%) | A = 1/G = 3,737 (0.027%) | A = 1/G = 10,757 (0.0092%) | 734 | 245 | Asn/Ser |
| 1:101705453 | rs146890331 | T/G | T = 1/G = 7,019 (0.014%) | T = 0/G = 3,738 (0%) | T = 1/G = 10,757 (0.0092%) | 913 | 305 | Cys/Gly |
| 1:101705535 | rsrs7549921 | G/C | G = 0/C = 7,020 (0%) | G = 2/C = 3,736 (0.054%) | G = 2/C = 10,756 (0.019%) | 995 | 332 | Arg/Pro |
| 1:101705565 | rs138199836 | C/G | C = 2/G = 7,018 (0.028%) | C = 0/G = 3,738 (0%) | C = 2/G = 10,756 (0.019%) | 1,025 | 342 | Pro/Arg |
| 1:101705579 | rs375635245 | A/G | A = 1/G = 7,019 (0.014%) | A = 0/G = 3,734 (0%) | A = 1/G = 10,753 (0.0092%) | 1,039 | 347 | Ser/Gly |
| 1:101705591 | rs149581242 | G/A | G = 0/A = 7,010 (0%) | G = 1/A = 3,735 (0.027%) | G = 1/A = 10,745 (0.0093%) | 1,051 | 351 | Cly/Ser |
The allele numbers in the European American (EA allele) and African American (AA allele) population are shown, as well as the total allele number as of June 2012.